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HISTOLOGY OF DENTAL PULP HEALING AFTER TOOTH REPLANTATION IN RATS

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°íÀºÁø, Á¤ÇѼº, ±èÀǼº, Á¤ÀÏ¿µ, À̽ÂÁ¾,
¼Ò¼Ó »ó¼¼Á¤º¸
°íÀºÁø ( Go Eun-Jin ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç
Á¤ÇѼº ( Jung Han-Sung ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­»ý¹°Çб³½Ç
±èÀǼº ( Kim Eui-Seong ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç
Á¤ÀÏ¿µ ( Jung Il-Young ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç
À̽ÂÁ¾ ( Lee Seung-Jong ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç

Abstract

º» ¿¬±¸ÀÇ ¸ñÀûÀº Èò Áã(rat)¸¦ ÀÌ¿ëÇÏ¿© ¹Ì¼º¼÷ ´Ü°èÀÇ Ä¡¾Æ¸¦ ¹ßÄ¡ ÈÄ Áï½Ã Àç½Ä ÇÏ¿´À» ¶§ ³ªÅ¸³ª´Â Ä¡¼öÀÇ Ä¡À¯ ¾ç»óÀ» Á¶Á÷ÇÐÀûÀ¸·Î °üÂûÇÏ°íÀÚ ÇÏ´Â °ÍÀÌ´Ù. »ýÈÄ 4ÁÖµÈ ¾ÏÄÆ Sprague-Dawley °è ÈòÁãÀÇ »ó¾Ç ¿ìÃø Á¦1´ë±¸Ä¡¸¦ ¹ß°Å ÈÄ ¿ø·¡ÀÇ Ä¡Á¶°ñ¿Í ³»·Î À§Ä¡½ÃÄ×´Ù. Àç½Ä ÈÄ 3ÀÏ°ºÎÅÍ ±¹¼ÒÀûÀ¸·Î Ä¡¼ö ³» ¿°Áõ ¼Ò°ßÀÌ °üÂûµÇ¾úÀ¸³ª, Ä¡±Ù ºÎÀ§¿¡¼­´Â ÀÌ¹Ì Ä¡¼öÀÇ ÀçÇ÷°üÈ­ ¹× Ä¡À¯°¡ ÁøÇàµÇ°í ÀÖ´Â ¼Ò°ßÀÌ °üÂûµÇ¾ú´Ù. Àç½Ä ÈÄ 5ÀÏ°ºÎÅÍ´Â odontoblast-like cellÀÌ °üÂûµÇ±â ½ÃÀÛÇÏ¿´´Ù. »ïÂ÷ »ó¾ÆÁúÀÇ Çü¼ºÀº Àç½Ä ÈÄ 1ÁÖ°ºÎÅÍ °üÂûµÇ±â ½ÃÀÛÇÏ¿´À¸¸ç, 2ÁÖ°ºÎÅÍ´Â È®½ÇÈ÷ °üÂûÇÒ ¼ö ÀÖ¾ú´Ù. Odontoblast-like cell ¹× »ïÂ÷»ó¾ÆÁú Çü¼ºÀº 4ÁÖ°±îÁöµµ °è¼Ó °üÂûµÇ¾ú´Ù. Àç½Ä ÈÄ 4ÁÖ°¿¡´Â bone-like tissue ¹× cementum-like tissueÀÌ Çü¼ºµÇ¾úÀ½À» °üÂûÇÏ¿´´Ù. º» ½ÇÇèÀ» ÅëÇÏ¿© Èò Áã Ä¡¾Æ Àç½Ä ½Ã ¼®È¸È­ °úÁ¤Àº Ãʱ⿡´Â »ïÂ÷»ó¾ÆÁú ħÂø¿¡ ÀÇÇؼ­ ÁøÇàµÇ³ª, ½Ã°£ÀÌ °æ°úÇϸ鼭 Á¡Â÷ bone-like tissue ¶Ç´Â cementum-like tissue°¡ Â÷ÁöÇÏ´Â ºñÀ²ÀÌ Áõ°¡ÇÏ´Â °ÍÀ» °üÂûÇÏ¿´´Ù.

The objective of this study was to observe the histology of dental pulp healing after tooth replantation in rats. The maxillary right first molars of 4-week-old rat were extracted, and then the teeth were repositioned in the original socket. At 3 days after replantation, there was localized inflammatory reaction. But, pulp revasculization and healing had already begun in the root area. At 5 days after replantation, odontoblast-like cells were observed. Tertiary dentin deposition was observed beneath the pulp-dentin border from 1 week after replantation. And tertiary dentin was increased at 2 weeks after replantation. The presence of odontoblast-like cells and the formation of tertiary dentin were continued to 4 weeks after replantation. At 4 weeks after replantation, the deposition of bone-like tissues and cementum-like tissues was observed. This results show that there is a possibility of pulp healing after tooth replantation in rats and the mineralization of tooth can progress. The mineralization of tooth after replantation was initially occurred by the deposition of tertiary dentin, but as time passed, the deposition of bone-like tissues and cementum-like tissues was begun and increased.

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»ïÂ÷»ó¾ÆÁú; °ñ; Ä¡¼ö Ä¡À¯; Ä¡¾Æ Àç½Ä; Áã
Tertiary dentin; Bone; Dental pulp healing; Tooth replantation; Rat

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